Gerhardt Müller-Goldboom was born in London and grew up in Berlin. He studied composition, musicology and double bass, also in Berlin. After a scholarship period at the Karajan Academy of the Berlin Philharmonic Orchestra, he began his musical career as an instrumentalist and was a member of the Deutsches Symphonie-Orchester Berlin for several years. Today he works as a composer and conductor.

His works have been performed at international festivals for contemporary music. The AKO Studio in Tokyo and the Experimental Intermedia Festival New York have dedicated portrait concerts to him. His list of works includes compositions for conventional instruments in various formations as well as electronic realisations. He is currently writing an opera based on Ovid's Metamorphoses.

As a conductor, Müller-Goldboom, who has experience as Kent Nagano's assistant, is mainly dedicated to contemporary music and has premièred numerous works. He is co-founder and has since been director of the ensemble work in progress – Berlin and has guest-conducted numerous formations in Germany and abroad. His opera performances of Pousseur's ‘Votre Faust’ and Marc André's ‘...22,13...’ have attracted international attention. He is also committed to older music. In 2019, he was the first German conductor to lead the Jerusalem Symphony Orchestra's Holocaust Memorial Concert, which included works by Joseph Haydn and Gustav Mahler.